IGSF9B

Across TCGA patient cohorts, IGSF9B mutation is significantly associated with the RNA expression of many other genes, with 5,760 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible IGSF9B-associated genes across cancer lineages are AOC2, BCCIP, and RPARP-AS1. Each is linked with IGSF9B in more than 4 cancer types. Because this analysis shows association rather than direction, both IGSF9B-to-partner and partner-to-IGSF9B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, AOC2 grouped by IGSF9B-low versus IGSF9B-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IGSF9B→partner) and Y-score (partner→IGSF9B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	AOC2 →	+1.073	+3.732	<.001	<.001	3	5
LIHC	BCCIP →	+0.484	+3.329	.001	.005	3	4
STAD	RPARP-AS1 →	+0.639	+3.219	<.001	.008	3	4
LUAD	WFDC21P →	-1.149	-4.075	.001	<.001	3	4
UCEC	CHEK1 →	+0.514	+1.360	<.001	<.001	3	4
COAD	SRP19 →	+0.403	+2.099	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,760 associations by consensus.

AOC2 by IGSF9B expression — BLCA

Explore this box plot interactively →