IGSF9B

Across TCGA cell cohorts, IGSF9B RNA expression is significantly associated with the go_rna of many other GO terms, with 3,882 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible IGSF9B-associated GO terms across cancer lineages are Negative regulation of gene expression, epigenetic, RNA catabolic process, and Protein localization to chromosome, telomeric region. Each is linked with IGSF9B in more than 10 cancer types. Because this analysis shows association rather than direction, both IGSF9B-to-partner and partner-to-IGSF9B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of gene expression, epigenetic grouped by IGSF9B-low versus IGSF9B-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IGSF9B→partner) and Y-score (partner→IGSF9B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Negative regulation of gene expression, epigenetic →	+0.038	+1.112	.005	<.001	3	10
BONE	RNA catabolic process →	+0.065	+1.200	.006	.004	2	11
LUNG_SCLC	Protein localization to chromosome, telomeric region →	+0.086	+1.198	.002	.008	3	9
LUNG_SCLC	Microtubule organizing center organization →	+0.076	+1.623	<.001	<.001	3	9
LUNG_SCLC	Negative regulation of syncytium formation by plasma membrane fusion →	+0.095	+1.585	<.001	<.001	3	9
BONE	Negative regulation of RNA splicing →	+0.082	+1.324	.005	.002	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,882 associations by consensus.

Negative regulation of gene expression, epigenetic by IGSF9B expression — PANCREAS

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