IGSF9B

Across TCGA cell cohorts, IGSF9B mutation is significantly associated with the RNA expression of many other genes, with 989 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible IGSF9B-associated genes across cancer lineages are SUV39H2, NF2, and MMS19. Each is linked with IGSF9B in more than 2 cancer types. Because this analysis shows association rather than direction, both IGSF9B-to-partner and partner-to-IGSF9B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SUV39H2 grouped by IGSF9B-low versus IGSF9B-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IGSF9B→partner) and Y-score (partner→IGSF9B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	SUV39H2 →	+0.726	+3.067	<.001	.009	3	3
BLOOD_Leukemia	NF2 →	+0.527	+3.199	.002	.007	3	3
LARGE_INTESTINE	MMS19 →	+0.398	+2.451	.007	.009	3	3
BLOOD_Lymphoma	GSTT4 →	+0.046	+3.669	<.001	.003	3	2
CNS	SULT2A1 →	+0.048	+4.321	<.001	.002	3	2
BREAST	SSMEM1 →	+0.100	+4.071	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 989 associations by consensus.

SUV39H2 by IGSF9B expression — LARGE_INTESTINE

Explore this box plot interactively →