IGSF9

Across TCGA patient cohorts, IGSF9 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,902 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible IGSF9-associated proteins across cancer lineages are GTF3C4, TRIM28_S697, and ZNF462_S2172. Each is linked with IGSF9 in more than 5 cancer types. Because this analysis shows association rather than direction, both IGSF9-to-partner and partner-to-IGSF9 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IGSF9 versus GTF3C4 in LSCC, with a Pearson correlation of 0.54.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IGSF9→partner) and Y-score (partner→IGSF9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	GTF3C4 →	+0.312	+1.301	<.001	<.001	3	6
LSCC	TRIM28_S697 →	+0.838	+0.908	<.001	<.001	3	5
LSCC	ZNF462_S2172 →	+0.560	+1.216	<.001	<.001	3	5
LSCC	IGSF9_S809 →	+1.242	+1.454	<.001	<.001	3	5
LSCC	MSH2 →	+0.486	+1.349	<.001	<.001	3	5
LSCC	ORC5 →	+0.295	+1.146	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,902 associations by consensus.

IGSF9 vs GTF3C4 — LSCC

Explore this scatter interactively →