IGSF9

Across TCGA cell cohorts, IGSF9 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,155 significant associations in total. BONE shows the largest number of these associations.

The most reproducible IGSF9-associated GO terms across cancer lineages are Negative regulation of mRNA catabolic process, Negative regulation of mRNA metabolic process, and Regulation of DNA-templated transcription elongation. Each is linked with IGSF9 in more than 13 cancer types. Because this analysis shows association rather than direction, both IGSF9-to-partner and partner-to-IGSF9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of mRNA catabolic process grouped by IGSF9-low versus IGSF9-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IGSF9→partner) and Y-score (partner→IGSF9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Negative regulation of mRNA catabolic process →	+0.072	+2.302	<.001	<.001	3	14
OESOPHAGUS	Negative regulation of mRNA metabolic process →	+0.072	+1.944	.005	<.001	3	12
BONE	Regulation of DNA-templated transcription elongation →	+0.099	+2.171	<.001	<.001	3	11
BONE	Regulation of RNA splicing →	+0.109	+2.267	<.001	<.001	3	11
BONE	Cell surface receptor signaling pathway via STAT →	-0.083	-1.818	<.001	<.001	3	11
BONE	Negative regulation of RNA catabolic process →	+0.084	+2.318	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,155 associations by consensus.

Negative regulation of mRNA catabolic process by IGSF9 expression — OVARY

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