IGSF10

Across TCGA patient cohorts, IGSF10 protein abundance is significantly associated with the RNA expression of many other genes, with 1,054 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible IGSF10-associated genes across cancer lineages are PDK2, GSTZ1, and EEF1A2. Each is linked with IGSF10 in more than 1 cancer types. Because this analysis shows association rather than direction, both IGSF10-to-partner and partner-to-IGSF10 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IGSF10 versus PDK2 in UCEC, with a Pearson correlation of -0.62.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IGSF10→partner) and Y-score (partner→IGSF10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PDK2 →	-0.560	-1.026	.007	.007	3	2
HNSC	GSTZ1 →	-0.471	-0.424	.009	.006	3	1
HNSC	EEF1A2 →	-1.968	-0.592	.002	.006	3	1
HNSC	DUSP22 →	-0.406	-0.702	.001	.001	3	1
HNSC	ABCD4 →	-0.348	-0.649	.004	.001	3	1
HNSC	ATP8B3 →	-0.506	-0.457	.004	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,054 associations by consensus.

IGSF10 vs PDK2 — UCEC

Explore this scatter interactively →