IGSF10

Across TCGA cell cohorts, IGSF10 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,051 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible IGSF10-associated GO terms across cancer lineages are Translational initiation, Negative regulation of DNA-templated transcription, elongation, and Purine nucleoside triphosphate metabolic process. Each is linked with IGSF10 in more than 7 cancer types. Because this analysis shows association rather than direction, both IGSF10-to-partner and partner-to-IGSF10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Translational initiation grouped by IGSF10-low versus IGSF10-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IGSF10→partner) and Y-score (partner→IGSF10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Translational initiation →	+0.056	+0.660	.003	.003	3	8
STOMACH	Negative regulation of DNA-templated transcription, elongation →	+0.108	+0.927	.001	.003	3	7
OVARY	Purine nucleoside triphosphate metabolic process →	+0.061	+0.510	<.001	.001	3	7
BLOOD_Leukemia	Schwann cell development →	+0.058	+1.124	<.001	.001	3	7
UPPER_AERODIGESTIVE_TRACT	Nucleoside triphosphate biosynthetic process →	+0.058	+0.357	.001	.003	3	7
STOMACH	Negative regulation of platelet-derived growth factor receptor signaling pathway →	+0.147	+0.694	<.001	.002	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,051 associations by consensus.

Translational initiation by IGSF10 expression — STOMACH

Explore this box plot interactively →