IGSF10

Across TCGA cell cohorts, IGSF10 mutation is significantly associated with the RNA expression of many other genes, with 1,686 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible IGSF10-associated genes across cancer lineages are ACER1, LYG1, and ACBD5. Each is linked with IGSF10 in more than 2 cancer types. Because this analysis shows association rather than direction, both IGSF10-to-partner and partner-to-IGSF10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ACER1 grouped by IGSF10-low versus IGSF10-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IGSF10→partner) and Y-score (partner→IGSF10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	ACER1 →	+0.050	+2.936	<.001	.007	3	3
LARGE_INTESTINE	LYG1 →	+1.025	+2.502	<.001	<.001	3	3
LARGE_INTESTINE	ACBD5 →	+0.682	+2.584	<.001	.001	3	3
LARGE_INTESTINE	RSAD1 →	+0.604	+1.483	.001	.002	3	3
LARGE_INTESTINE	SLC39A6 →	+0.815	+1.871	<.001	.002	3	3
LARGE_INTESTINE	OXSM →	+0.469	+2.222	.004	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,686 associations by consensus.

ACER1 by IGSF10 expression — SOFT_TISSUE

Explore this box plot interactively →