IGLVVI-25-1

Across TCGA pan-cancer cohorts, IGLVVI-25-1 RNA is linked to patient survival in 10 of 34 cancer types, making it the most broadly survival-associated IGLVVI-25-1 data layer.

The strongest signal is observed in esophageal carcinoma (ESCA), where higher IGLVVI-25-1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated IGLVVI-25-1 expression acts as an unfavorable survival marker, although some lineages such as CHOL and LUAD show a favorable association.

ESCA, BLCA, and STAD are the cancer types where IGLVVI-25-1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ESCA	OS	Tertile	All	0.198	0.872	.003	36	view →
BLCA	DFS	Tertile	IV	0.126	0.479	.007	27	view →
STAD	DFS	Tertile	II,III,IV	0.396	0.708	.002	27	view →
LIHC	OS	Tertile	III,IV	0.327	0.648	.007	21	view →
UCEC	DFS	Tertile	All	0.762	0.898	.020	18	view →
HNSC	OS	Tertile	All	0.177	0.710	.016	18	view →
CHOL	DFS	Tertile	All	1.000	0.291	.035	9	view →
SARC	OS	Tertile	All	0.162	0.767	.002	9	view →
LUAD	OS	Tertile	II,III,IV	1.000	0.722	.022	6	view →
READ	OS	Tertile	III,IV	0.638	0.900	.021	6	view →

Pink = unfavorable, green = favorable. Showing the 10 strongest of 10 lineages.

IGLVVI-25-1–ESCA (OS)

Open the ESCA breakdown →