Across TCGA patient cohorts, IGLV7-46 protein abundance is significantly associated with the RNA expression of many other genes, with 6,170 significant associations in total. GBM shows the largest number of these associations.

The most reproducible IGLV7-46-associated genes across cancer lineages are NCF4, ARHGAP9, and PRR33. Each is linked with IGLV7-46 in more than 4 cancer types. Because this analysis shows association rather than direction, both IGLV7-46-to-partner and partner-to-IGLV7-46 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IGLV7-46→partner) and Y-score (partner→IGLV7-46) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	NCF4 →	+1.045	+0.742	.001	<.001	3	5
COAD	ARHGAP9 →	+0.937	+0.626	.001	.006	3	4
COAD	PRR33 →	+0.664	+0.608	<.001	.001	3	4
OV	P2RY10 →	+0.840	+0.766	<.001	<.001	3	4
COAD	LINC01857 →	+0.989	+0.653	.005	.002	3	4
GBM	GMFG →	+0.915	+1.106	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,170 associations by consensus.

Exploration

IGLV7-46 survival (RNA) · tumor vs normal (RNA) · all IGLV7-46 data types