IGLV7-43

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, IGLV7-43 mutation is significantly associated with the RNA expression of many other genes, with 59 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible IGLV7-43-associated genes across cancer lineages are RN7SL55P, RNA5SP113, and OR13C3. Each is linked with IGLV7-43 in more than 1 cancer types. Because this analysis shows association rather than direction, both IGLV7-43-to-partner and partner-to-IGLV7-43 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IGLV7-43→partner) and Y-score (partner→IGLV7-43) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKCMRN7SL55P →+0.125+4.034.002.00432
UCECRNA5SP113 →+1.438+4.641<.001.00632
SKCMOR13C3 →+0.028+4.495<.001.00732
LUADMIR548X2 →+0.688+7.930<.001.00831
BLCAIGLJ4 →+1.101+7.640<.001.00931
SKCMH2AZP5 →+0.111+4.075<.001.00431
Each partner links to its Q-omics profile. Showing the 6 strongest of 59 associations by consensus.

Exploration