IGLV6-57

RNA expression — cross-omics
Cross-omicsRNA → MUTATIONPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, IGLV6-57 RNA expression is significantly associated with the mutation status of many other genes, with 10,119 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible IGLV6-57-associated genes across cancer lineages are TP53, KRAS, and TTN. Each is linked with IGLV6-57 in more than 3 cancer types. Because this analysis shows association rather than direction, both IGLV6-57-to-partner and partner-to-IGLV6-57 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IGLV6-57→partner) and Y-score (partner→IGLV6-57) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
STADTP53 →-1.027-0.902<.001.00134
PAADKRAS →-1.432-1.127.001.00134
LUSCTTN →-0.475-0.791.001<.00133
UCECCNTN1 →+2.187+1.309<.001<.00133
UCECSETX →+1.353+1.483<.001<.00133
UCECTRPC5 →+2.078+1.669<.001<.00133
Each partner links to its Q-omics profile. Showing the 6 strongest of 10,119 associations by consensus.

Exploration