Across TCGA patient cohorts, IGLV5-52 protein abundance is significantly associated with the RNA expression of many other genes, with 125 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible IGLV5-52-associated genes across cancer lineages are WDR44, MORC4, and TNFAIP8. Each is linked with IGLV5-52 in more than 1 cancer types. Because this analysis shows association rather than direction, both IGLV5-52-to-partner and partner-to-IGLV5-52 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IGLV5-52→partner) and Y-score (partner→IGLV5-52) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	WDR44 →	-0.553	-1.605	.009	.006	3	1
LUAD	MORC4 →	-0.618	-1.506	.006	.007	3	1
LUAD	TNFAIP8 →	-0.546	-1.343	.009	.001	3	1
LUAD	ELOVL7 →	-1.051	-1.219	.001	<.001	3	1
LUAD	ANGPTL4 →	-1.590	-1.644	.008	.002	3	1
LUAD	MYLPF →	-0.384	-1.462	.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 125 associations by consensus.

Exploration

IGLV5-52 survival (RNA) · tumor vs normal (RNA) · all IGLV5-52 data types