Across TCGA pan-cancer cohorts, IGLV5-37 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated IGLV5-37 data layer compared with 24 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher IGLV5-37 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated IGLV5-37 expression acts as an unfavorable survival marker, although some lineages such as LUAD and LSCC show a favorable association.

LUAD, LSCC, and GBM are the cancer types where IGLV5-37 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	DFS	Tertile	All	1.000	0.265	.002	18	view →
LSCC	DFS	Tertile	All	1.000	0.374	.024	4	view →
GBM	OS	Median	All	0.478	0.932	.038	3	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

Exploration

Same gene, other analysis: IGLV5-37 tumor-vs-normal RNA expression · all IGLV5-37 data types