Across TCGA patient cohorts, IGLV5-37 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,961 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible IGLV5-37-associated GO terms across cancer lineages are B cell receptor signaling pathway, Complement activation, and Complement activation, classical pathway. Each is linked with IGLV5-37 in more than 29 cancer types. Because this analysis shows association rather than direction, both IGLV5-37-to-partner and partner-to-IGLV5-37 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IGLV5-37→partner) and Y-score (partner→IGLV5-37) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CHOL	B cell receptor signaling pathway →	+0.095	+2.061	<.001	<.001	3	30
THCA	Complement activation →	+0.146	+1.216	<.001	<.001	3	28
THCA	Complement activation, classical pathway →	+0.185	+1.248	<.001	<.001	3	27
LAML	B cell mediated immunity →	+0.089	+1.726	<.001	<.001	3	27
THCA	Antibacterial humoral response →	+0.161	+1.309	<.001	<.001	3	27
STAD	Immunoglobulin production →	+0.077	+1.623	<.001	<.001	3	27

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,961 associations by consensus.

Exploration

IGLV5-37 survival (RNA) · tumor vs normal (RNA) · all IGLV5-37 data types