Across TCGA patient cohorts, IGLV4-69 protein abundance is significantly associated with the RNA expression of many other genes, with 10,093 significant associations in total. GBM shows the largest number of these associations.

The most reproducible IGLV4-69-associated genes across cancer lineages are IGKV3-20, IGLL5, and IGLV6-57. Each is linked with IGLV4-69 in more than 6 cancer types. Because this analysis shows association rather than direction, both IGLV4-69-to-partner and partner-to-IGLV4-69 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IGLV4-69→partner) and Y-score (partner→IGLV4-69) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	IGKV3-20 →	+3.422	+1.397	.001	.001	3	7
LSCC	IGLL5 →	+1.215	+0.570	<.001	.002	3	6
BRCA	IGLV6-57 →	+2.792	+1.024	<.001	<.001	3	6
BRCA	IGLV2-14 →	+2.018	+0.875	<.001	<.001	3	6
OV	IGHG1 →	+3.573	+1.019	<.001	.001	3	6
OV	IGHV1-69D →	+2.682	+0.870	<.001	.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,093 associations by consensus.

Exploration

IGLV4-69 survival (RNA) · tumor vs normal (RNA) · all IGLV4-69 data types