Across TCGA patient cohorts, IGLV4-60 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,052 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible IGLV4-60-associated GO terms across cancer lineages are Antibacterial humoral response, Antimicrobial humoral response, and Humoral immune response mediated by circulating immunoglobulin. Each is linked with IGLV4-60 in more than 31 cancer types. Because this analysis shows association rather than direction, both IGLV4-60-to-partner and partner-to-IGLV4-60 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IGLV4-60→partner) and Y-score (partner→IGLV4-60) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
THCA	Antibacterial humoral response →	+0.162	+3.057	<.001	<.001	3	32
CHOL	Antimicrobial humoral response →	+0.112	+2.503	<.001	<.001	3	31
THCA	Humoral immune response mediated by circulating immunoglobulin →	+0.158	+2.887	<.001	<.001	3	31
CHOL	B cell receptor signaling pathway →	+0.083	+2.349	<.001	<.001	3	30
CHOL	Respiratory burst →	+0.095	+2.353	<.001	<.001	3	29
THCA	Complement activation →	+0.150	+2.897	<.001	<.001	3	29

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,052 associations by consensus.

Exploration

IGLV4-60 survival (RNA) · tumor vs normal (RNA) · all IGLV4-60 data types