Across TCGA patient cohorts, IGLV3-32 mutation is significantly associated with the RNA expression of many other genes, with 31 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible IGLV3-32-associated genes across cancer lineages are GYG1P2, MTND5P20, and NREP-AS1. Each is linked with IGLV3-32 in more than 1 cancer types. Because this analysis shows association rather than direction, both IGLV3-32-to-partner and partner-to-IGLV3-32 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IGLV3-32→partner) and Y-score (partner→IGLV3-32) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	GYG1P2 →	+0.057	+5.037	<.001	.009	3	1
SKCM	MTND5P20 →	+0.418	+5.362	<.001	.005	3	1
SKCM	NREP-AS1 →	+0.055	+5.594	<.001	.004	3	1
LUAD	SNORA70J →	+0.589	+5.217	<.001	.007	3	1
LUAD	SNORA70E →	+0.488	+5.217	.009	.007	3	1
LUAD	E2F6P2 →	+0.095	+5.481	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 31 associations by consensus.

Exploration

IGLV3-32 survival (RNA) · tumor vs normal (RNA) · all IGLV3-32 data types