IGLV3-22

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, IGLV3-22 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,243 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible IGLV3-22-associated GO terms across cancer lineages are B cell mediated immunity, Antimicrobial humoral response, and Antibacterial humoral response. Each is linked with IGLV3-22 in more than 26 cancer types. Because this analysis shows association rather than direction, both IGLV3-22-to-partner and partner-to-IGLV3-22 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IGLV3-22→partner) and Y-score (partner→IGLV3-22) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
THCAB cell mediated immunity →+0.099+0.259<.001<.001327
THCAAntimicrobial humoral response →+0.110+0.242<.001<.001326
THCAAntibacterial humoral response →+0.164+0.244<.001<.001326
ESCAImmunoglobulin production →+0.076+0.534<.001<.001326
THCAHumoral immune response mediated by circulating immunoglobulin →+0.153+0.237<.001<.001325
SKCMB cell receptor signaling pathway →+0.078+0.499<.001<.001325
Each partner links to its Q-omics profile. Showing the 6 strongest of 6,243 associations by consensus.

Exploration