Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts
Across TCGA patient cohorts, IGLV3-21 mutation is significantly associated with the RNA expression of many other genes, with 45 significant associations in total. SKCM shows the largest number of these associations.
The most reproducible IGLV3-21-associated genes across cancer lineages are RN7SL39P, NMBR-AS1, and RN7SL764P. Each is linked with IGLV3-21 in more than 1 cancer types. Because this analysis shows association rather than direction, both IGLV3-21-to-partner and partner-to-IGLV3-21 results are reported.
Each partner links to its own Q-omics profile.
mutation associated genes by consensus
Ranked by combined sampling and lineage consensus. X-score (IGLV3-21→partner) and Y-score (partner→IGLV3-21) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.