Across TCGA patient cohorts, IGLV3-16 mutation is significantly associated with the RNA expression of many other genes, with 61 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible IGLV3-16-associated genes across cancer lineages are TUBAP8, RN7SL492P, and LINC01743. Each is linked with IGLV3-16 in more than 1 cancer types. Because this analysis shows association rather than direction, both IGLV3-16-to-partner and partner-to-IGLV3-16 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IGLV3-16→partner) and Y-score (partner→IGLV3-16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	TUBAP8 →	+0.057	+3.015	<.001	.009	3	1
SKCM	RN7SL492P →	+0.117	+3.947	<.001	.002	3	1
SKCM	LINC01743 →	+0.059	+3.071	.005	.008	3	1
SKCM	MARK2P17 →	+0.090	+3.255	.001	.005	3	1
SKCM	RN7SL380P →	+0.112	+3.744	<.001	.003	3	1
SKCM	LINC02758 →	+0.092	+3.809	.004	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 61 associations by consensus.

Exploration

IGLV3-16 survival (RNA) · tumor vs normal (RNA) · all IGLV3-16 data types