Across TCGA patient cohorts, IGLV3-10 mutation is significantly associated with the RNA expression of many other genes, with 18 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible IGLV3-10-associated genes across cancer lineages are SNORD113-3, RN7SKP101, and MIR6864. Each is linked with IGLV3-10 in more than 1 cancer types. Because this analysis shows association rather than direction, both IGLV3-10-to-partner and partner-to-IGLV3-10 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IGLV3-10→partner) and Y-score (partner→IGLV3-10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
DLBC	SNORD113-3 →	+0.762	+4.874	<.001	.008	3	1
DLBC	RN7SKP101 →	+0.176	+4.874	<.001	.008	3	1
UCEC	MIR6864 →	+0.903	+3.061	<.001	.008	3	1
LUAD	PAICSP5 →	+0.074	+5.044	<.001	.009	3	1
LUAD	VTRNA2-2P →	+0.655	+5.554	<.001	.004	3	1
UCEC	SNX3P1Y →	+0.256	+6.156	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 18 associations by consensus.

Exploration

IGLV3-10 survival (RNA) · tumor vs normal (RNA) · all IGLV3-10 data types