IGLV2-14

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, IGLV2-14 mutation is significantly associated with the immune_cell of many other genes, with 2 significant associations in total. LUSC shows the largest number of these associations.

The most reproducible IGLV2-14-associated genes across cancer lineages are Fibroblasts and CD4+ Tcm. Each is linked with IGLV2-14 in more than 1 cancer types. Because this analysis shows association rather than direction, both IGLV2-14-to-partner and partner-to-IGLV2-14 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IGLV2-14→partner) and Y-score (partner→IGLV2-14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
COADFibroblasts →+0.025+5.721.044.03631
LUSCCD4+ Tcm →+0.009+5.593.004.03031
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

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