Across TCGA patient cohorts, IGLV10-54 protein abundance is significantly associated with the RNA expression of many other genes, with 4,703 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible IGLV10-54-associated genes across cancer lineages are ATL2, TLK2, and MIOS. Each is linked with IGLV10-54 in more than 1 cancer types. Because this analysis shows association rather than direction, both IGLV10-54-to-partner and partner-to-IGLV10-54 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IGLV10-54→partner) and Y-score (partner→IGLV10-54) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	ATL2 →	-0.407	-1.040	.005	.002	3	2
LSCC	TLK2 →	-0.413	-1.242	.001	.001	3	2
LSCC	MIOS →	-0.411	-1.497	<.001	<.001	3	2
LUAD	LRRC34 →	-0.715	-1.737	.003	<.001	3	2
LSCC	LINC02878 →	-0.420	-1.288	.002	.002	3	2
LSCC	TCTE3 →	-0.572	-0.999	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,703 associations by consensus.

Exploration

IGLV10-54 survival (RNA) · tumor vs normal (RNA) · all IGLV10-54 data types