Across TCGA pan-cancer cohorts, IGLV1-47 Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated IGLV1-47 data layer compared with 26 for mass-spec protein and 5 for mass-spec protein.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher IGLV1-47 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated IGLV1-47 expression acts as an unfavorable survival marker.

COAD, LUAD, and UCEC are the cancer types where IGLV1-47 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	OS	Median	All	0.168	0.806	.002	24	view →
LUAD	OS	Median	All	0.542	0.812	<.001	19	view →
UCEC	OS	Median	IV	0.066	0.755	<.001	12	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

Exploration

Same gene, other analysis: IGLV1-47 tumor-vs-normal RNA expression · all IGLV1-47 data types