Across TCGA pan-cancer cohorts, IGLV1-44 Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated IGLV1-44 data layer compared with 22 for mass-spec protein and 8 for mass-spec protein.

The strongest signal is observed in stomach adenocarcinoma (STAD), where higher IGLV1-44 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated IGLV1-44 expression acts as an unfavorable survival marker.

STAD and BLCA are the cancer types where IGLV1-44 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
STAD	OS	Median	All	0.074	0.667	<.001	45	view →
BLCA	DFS	Median	All	0.163	0.625	.018	15	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: IGLV1-44 tumor-vs-normal RNA expression · all IGLV1-44 data types