Across TCGA patient cohorts, IGLV1-40 protein abundance is significantly associated with the protein abundance of many other proteins, with 17,595 significant associations in total. GBM shows the largest number of these associations.

The most reproducible IGLV1-40-associated proteins across cancer lineages are IGHG1, IGHG2, and IGHG3. Each is linked with IGLV1-40 in more than 9 cancer types. Because this analysis shows association rather than direction, both IGLV1-40-to-partner and partner-to-IGLV1-40 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IGLV1-40→partner) and Y-score (partner→IGLV1-40) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	IGHG1 →	+0.826	+0.891	<.001	<.001	3	10
GBM	IGHG2 →	+0.952	+1.029	<.001	<.001	3	10
GBM	IGHG3 →	+0.750	+0.590	<.001	<.001	3	10
CCRCC	IGHV3-15 →	+0.904	+0.784	<.001	<.001	3	10
OV	IGHV3-49 →	+1.542	+1.350	<.001	<.001	3	10
GBM	IGHV3-7 →	+1.078	+0.889	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,595 associations by consensus.

Exploration

IGLV1-40 survival (RNA) · tumor vs normal (RNA) · all IGLV1-40 data types