Across TCGA patient cohorts, IGLV1-36 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,285 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible IGLV1-36-associated proteins across cancer lineages are MZB1, CD38, and TXNDC5. Each is linked with IGLV1-36 in more than 9 cancer types. Because this analysis shows association rather than direction, both IGLV1-36-to-partner and partner-to-IGLV1-36 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IGLV1-36→partner) and Y-score (partner→IGLV1-36) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	MZB1 →	+1.345	+2.206	<.001	<.001	3	10
BRCA	CD38 →	+0.860	+1.945	<.001	<.001	3	8
OV	TXNDC5 →	+0.597	+1.777	<.001	<.001	3	7
CCRCC	IRF4 →	+0.853	+2.532	.007	.002	3	7
LSCC	SEC11C →	+1.027	+1.915	<.001	<.001	3	7
OV	DOCK2 →	+0.563	+2.027	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,285 associations by consensus.

Exploration

IGLV1-36 survival (RNA) · tumor vs normal (RNA) · all IGLV1-36 data types