IGLON5

Across TCGA patient cohorts, IGLON5 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,148 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible IGLON5-associated proteins across cancer lineages are CCN1, FSCN1, and NRP2. Each is linked with IGLON5 in more than 4 cancer types. Because this analysis shows association rather than direction, both IGLON5-to-partner and partner-to-IGLON5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IGLON5 versus CCN1 in OV, with a Pearson correlation of 0.40.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IGLON5→partner) and Y-score (partner→IGLON5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	CCN1 →	+0.614	+0.957	<.001	<.001	3	5
BRCA	FSCN1 →	+0.719	+0.555	<.001	.003	3	5
BRCA	NRP2 →	+0.531	+0.537	<.001	.003	3	5
OV	PSMB5 →	+0.445	+1.087	.003	.003	3	4
BRCA	PLOD3 →	+0.472	+0.342	<.001	<.001	3	4
PDAC	SLC16A3 →	+0.522	+0.315	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,148 associations by consensus.

IGLON5 vs CCN1 — OV

Explore this scatter interactively →