IGLON5

Across TCGA patient cohorts, IGLON5 protein abundance is significantly associated with the RNA expression of many other genes, with 5,257 significant associations in total. GBM shows the largest number of these associations.

The most reproducible IGLON5-associated genes across cancer lineages are YPEL1, SNRPD3, and PRODH. Each is linked with IGLON5 in more than 1 cancer types. Because this analysis shows association rather than direction, both IGLON5-to-partner and partner-to-IGLON5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IGLON5 versus YPEL1 in GBM, with a Pearson correlation of 0.29.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IGLON5→partner) and Y-score (partner→IGLON5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	YPEL1 →	+0.468	+0.471	.008	.004	3	1
GBM	SNRPD3 →	+0.500	+0.677	<.001	<.001	3	1
GBM	PRODH →	+0.768	+0.418	.003	.005	3	1
GBM	CYTH4 →	-0.763	-0.637	.001	<.001	3	1
GBM	GRK3 →	+0.391	+0.480	.008	.001	3	1
GBM	SEZ6L →	+2.278	+0.716	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,257 associations by consensus.

IGLON5 vs YPEL1 — GBM

Explore this scatter interactively →