IGLON5

Across TCGA patient cohorts, IGLON5 mutation is significantly associated with the immune_cell of many other genes, with 3 significant associations in total. COAD shows the largest number of these associations.

The most reproducible IGLON5-associated genes across cancer lineages are Myocytes, Th2 cells, and Sebocytes. Each is linked with IGLON5 in more than 1 cancer types. Because this analysis shows association rather than direction, both IGLON5-to-partner and partner-to-IGLON5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Myocytes grouped by IGLON5-low versus IGLON5-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IGLON5→partner) and Y-score (partner→IGLON5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	Myocytes →	+0.041	+2.820	.039	.036	3	2
UCEC	Th2 cells →	+0.174	+2.459	.045	.020	3	1
COAD	Sebocytes →	+0.028	+2.834	.029	.035	1	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

Myocytes by IGLON5 expression — COAD

Explore this box plot interactively →