IGLON5

Across TCGA cell cohorts, IGLON5 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,173 significant associations in total. BONE shows the largest number of these associations.

The most reproducible IGLON5-associated GO terms across cancer lineages are Negative regulation of mRNA catabolic process, Purine nucleoside triphosphate metabolic process, and Purine ribonucleoside triphosphate metabolic process. Each is linked with IGLON5 in more than 8 cancer types. Because this analysis shows association rather than direction, both IGLON5-to-partner and partner-to-IGLON5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of mRNA catabolic process grouped by IGLON5-low versus IGLON5-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IGLON5→partner) and Y-score (partner→IGLON5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Negative regulation of mRNA catabolic process →	+0.063	+0.144	<.001	.007	3	9
BONE	Purine nucleoside triphosphate metabolic process →	+0.089	+1.046	<.001	.004	3	8
BONE	Purine ribonucleoside triphosphate metabolic process →	+0.094	+1.228	<.001	.003	3	8
OVARY	Negative regulation of mRNA metabolic process →	+0.075	+1.073	<.001	.004	3	7
LUNG_NSCLC_LUSC	Regulation of gamma-aminobutyric acid secretion →	+0.986	+0.380	<.001	.007	3	7
BONE	ATP metabolic process →	+0.071	+0.832	.002	.002	2	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,173 associations by consensus.

Negative regulation of mRNA catabolic process by IGLON5 expression — LARGE_INTESTINE

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