IGLL5

Across TCGA patient cohorts, IGLL5 protein abundance is significantly associated with the RNA expression of many other genes, with 16,641 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible IGLL5-associated genes across cancer lineages are IGLV2-23, IGHV3-21, and IGKV3-20. Each is linked with IGLL5 in more than 8 cancer types. Because this analysis shows association rather than direction, both IGLL5-to-partner and partner-to-IGLL5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IGLL5 versus IGLV2-23 in OV, with a Pearson correlation of 0.39.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IGLL5→partner) and Y-score (partner→IGLL5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	IGLV2-23 →	+3.453	+1.059	<.001	<.001	3	9
OV	IGHV3-21 →	+3.043	+1.065	.002	<.001	3	9
OV	IGKV3-20 →	+2.598	+0.719	<.001	<.001	3	9
LSCC	FCRL5 →	+1.375	+0.878	<.001	<.001	3	8
OV	IGKV3D-20 →	+2.581	+0.877	<.001	<.001	3	8
OV	IGLV1-44 →	+3.193	+0.845	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,641 associations by consensus.

IGLL5 vs IGLV2-23 — OV

Explore this scatter interactively →