IGLL5

Across TCGA cell cohorts, IGLL5 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,347 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible IGLL5-associated GO terms across cancer lineages are Neutrophil-mediated killing of fungus, ATP metabolic process, and Nucleoside triphosphate biosynthetic process. Each is linked with IGLL5 in more than 8 cancer types. Because this analysis shows association rather than direction, both IGLL5-to-partner and partner-to-IGLL5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Neutrophil-mediated killing of fungus grouped by IGLL5-low versus IGLL5-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IGLL5→partner) and Y-score (partner→IGLL5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Neutrophil-mediated killing of fungus →	+0.155	+0.147	<.001	<.001	3	9
BONE	ATP metabolic process →	+0.090	+0.179	<.001	.004	3	8
LUNG_NSCLC_LUAD	Nucleoside triphosphate biosynthetic process →	+0.053	+0.123	.001	.003	3	8
KIDNEY	Negative regulation of myoblast fusion →	+0.101	+0.130	<.001	.001	3	8
LARGE_INTESTINE	Purine ribonucleoside triphosphate metabolic process →	+0.040	+0.130	.003	.007	3	8
BREAST	Establishment of spindle localization →	+0.063	+0.150	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,347 associations by consensus.

Neutrophil-mediated killing of fungus by IGLL5 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →