IGLL4P

Across TCGA patient cohorts, IGLL4P RNA expression is significantly associated with the go_rna of many other GO terms, with 6,784 significant associations in total. THYM shows the largest number of these associations.

The most reproducible IGLL4P-associated GO terms across cancer lineages are Regulation of intrinsic apoptotic signaling pathway, Regulation of protein serine/threonine kinase activity, and Regulation of post-translational protein modification. Each is linked with IGLL4P in more than 10 cancer types. Because this analysis shows association rather than direction, both IGLL4P-to-partner and partner-to-IGLL4P results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of intrinsic apoptotic signaling pathway grouped by IGLL4P-low versus IGLL4P-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IGLL4P→partner) and Y-score (partner→IGLL4P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Regulation of intrinsic apoptotic signaling pathway →	+0.065	+0.131	<.001	<.001	3	10
STAD	Regulation of protein serine/threonine kinase activity →	+0.053	+0.128	<.001	<.001	3	10
STAD	Regulation of post-translational protein modification →	+0.070	+0.141	<.001	<.001	3	10
STAD	Positive regulation of stress-activated protein kinase signaling cascade →	+0.042	+0.137	<.001	.002	2	11
STAD	Vacuole organization →	+0.066	+0.128	<.001	<.001	3	10
STAD	Mitotic nuclear membrane organization →	+0.067	+0.154	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,784 associations by consensus.

Regulation of intrinsic apoptotic signaling pathway by IGLL4P expression — STAD

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