IGLL1

Across TCGA patient cohorts, IGLL1 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,044 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible IGLL1-associated GO terms across cancer lineages are Regulation of B cell differentiation, Negative regulation of lymphocyte apoptotic process, and Leukocyte mediated cytotoxicity. Each is linked with IGLL1 in more than 23 cancer types. Because this analysis shows association rather than direction, both IGLL1-to-partner and partner-to-IGLL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of B cell differentiation grouped by IGLL1-low versus IGLL1-high in SKCM.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IGLL1→partner) and Y-score (partner→IGLL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	Regulation of B cell differentiation →	+0.080	+0.581	<.001	<.001	3	24
ESCA	Negative regulation of lymphocyte apoptotic process →	+0.061	+0.710	<.001	<.001	3	24
SKCM	Leukocyte mediated cytotoxicity →	+0.044	+0.553	<.001	<.001	3	23
ESCA	B cell mediated immunity →	+0.115	+1.135	<.001	<.001	3	23
ESCA	Negative regulation of response to biotic stimulus →	+0.049	+0.580	<.001	<.001	3	23
ESCA	T cell differentiation in thymus →	+0.054	+0.629	<.001	<.001	3	23

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,044 associations by consensus.

Regulation of B cell differentiation by IGLL1 expression — SKCM

Explore this box plot interactively →