IGLL1

Across TCGA patient cohorts, IGLL1 protein abundance is significantly associated with the RNA expression of many other genes, with 14,612 significant associations in total. GBM shows the largest number of these associations.

The most reproducible IGLL1-associated genes across cancer lineages are IRF4, IGHV5-51, and G0S2. Each is linked with IGLL1 in more than 6 cancer types. Because this analysis shows association rather than direction, both IGLL1-to-partner and partner-to-IGLL1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IGLL1 versus IRF4 in LSCC, with a Pearson correlation of 0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IGLL1→partner) and Y-score (partner→IGLL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	IRF4 →	+1.271	+0.448	<.001	<.001	3	7
OV	IGHV5-51 →	+2.581	+0.920	.004	<.001	3	6
GBM	G0S2 →	+1.573	+0.457	.001	.001	3	5
UCEC	FCRL5 →	+0.934	+0.331	<.001	<.001	3	5
OV	BMP6 →	+1.196	+0.847	<.001	<.001	3	5
OV	IGKC →	+3.471	+0.784	.006	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,612 associations by consensus.

IGLL1 vs IRF4 — LSCC

Explore this scatter interactively →