IGLL1

Across TCGA patient cohorts, IGLL1 mutation is significantly associated with the RNA expression of many other genes, with 143 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible IGLL1-associated genes across cancer lineages are OR11J5P, RNY1P1, and RN7SL853P. Each is linked with IGLL1 in more than 1 cancer types. Because this analysis shows association rather than direction, both IGLL1-to-partner and partner-to-IGLL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR11J5P grouped by IGLL1-low versus IGLL1-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IGLL1→partner) and Y-score (partner→IGLL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	OR11J5P →	+0.059	+7.640	<.001	.009	3	2
UCEC	RNY1P1 →	+0.250	+4.113	<.001	.001	3	2
SKCM	RN7SL853P →	+0.086	+4.900	<.001	.002	3	1
SKCM	MIR6815 →	+0.202	+4.212	<.001	.007	3	1
SKCM	RN7SL541P →	+0.092	+3.422	<.001	.006	3	1
SKCM	RN7SL837P →	+0.088	+4.408	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 143 associations by consensus.

OR11J5P by IGLL1 expression — BLCA

Explore this box plot interactively →