IGLL1

Across TCGA cell cohorts, IGLL1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,406 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible IGLL1-associated GO terms across cancer lineages are Negative regulation of RNA splicing, Negative regulation of translational initiation, and Neutrophil-mediated killing of fungus. Each is linked with IGLL1 in more than 8 cancer types. Because this analysis shows association rather than direction, both IGLL1-to-partner and partner-to-IGLL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of RNA splicing grouped by IGLL1-low versus IGLL1-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IGLL1→partner) and Y-score (partner→IGLL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Negative regulation of RNA splicing →	+0.065	+0.378	.001	.003	2	9
LARGE_INTESTINE	Negative regulation of translational initiation →	+0.046	+0.264	.004	.002	3	8
URINARY_TRACT	Neutrophil-mediated killing of fungus →	+0.193	+0.703	<.001	.002	3	7
LARGE_INTESTINE	Negative regulation of mRNA processing →	+0.068	+0.347	.001	.006	2	8
STOMACH	Cell division →	+0.059	+0.198	.003	.002	2	8
LARGE_INTESTINE	Response to forskolin →	+0.106	+0.278	.002	.004	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,406 associations by consensus.

Negative regulation of RNA splicing by IGLL1 expression — LARGE_INTESTINE

Explore this box plot interactively →