IGLL1

Across TCGA cell cohorts, IGLL1 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. BLOOD_Myeloma shows the largest number of these associations.

The most reproducible IGLL1-associated genes across cancer lineages are NHLH2 and C10orf67. Each is linked with IGLL1 in more than 1 cancer types. Because this analysis shows association rather than direction, both IGLL1-to-partner and partner-to-IGLL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NHLH2 grouped by IGLL1-low versus IGLL1-high in BLOOD_Myeloma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IGLL1→partner) and Y-score (partner→IGLL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	NHLH2 →	+0.006	+3.906	<.001	.009	3	1
BLOOD_Myeloma	C10orf67 →	+0.011	+4.285	.004	.003	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

NHLH2 by IGLL1 expression — BLOOD_Myeloma

Explore this box plot interactively →