Across TCGA pan-cancer cohorts, IGLJ6 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of IGLJ6’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where IGLJ6 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types IGLJ6 is over-expressed in tumor, although a few such as READ show the opposite, repressed pattern.

COAD, READ, and UCEC are the cancer types where IGLJ6 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in IGLJ6 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	Female	All	+1.247	.003	4	view →
READ	All	III,IV	−1.440	.013	2	view →
UCEC	All	All	+0.609	.045	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

Exploration

Same gene, other analysis: IGLJ6 RNA expression & survival · all IGLJ6 data types