IGLCOR22-1

Across TCGA pan-cancer cohorts, IGLCOR22-1 RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated IGLCOR22-1 data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher IGLCOR22-1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated IGLCOR22-1 expression acts as an unfavorable survival marker, although some lineages such as HNSC and OV show a favorable association.

ACC, UVM, and LIHC are the cancer types where IGLCOR22-1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	DFS	Tertile	All	0.128	0.613	<.001	93	view →
UVM	OS	Tertile	All	0.284	0.762	<.001	72	view →
LIHC	OS	Tertile	III,IV	0.442	0.692	.005	36	view →
HNSC	DFS	Tertile	All	0.801	0.679	.010	33	view →
THCA	OS	Tertile	III,IV	0.873	0.970	.009	33	view →
KIRP	DFS	Tertile	IV	0.033	0.525	.001	24	view →
OV	DFS	Tertile	III,IV	0.427	0.343	.019	20	view →
DLBC	OS	Tertile	II,III,IV	0.563	1.000	.008	18	view →
SARC	OS	Tertile	All	0.659	0.875	.005	18	view →
COAD	DFS	Tertile	III,IV	0.826	0.378	.020	15	view →
LUAD	DFS	Quartile	IV	0.860	0.535	.024	10	view →
READ	DFS	Quartile	IV	0.885	0.516	.029	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

IGLCOR22-1–ACC (DFS)

Open the ACC breakdown →