Across TCGA patient cohorts, IGLC7 mutation is significantly associated with the RNA expression of many other genes, with 99 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible IGLC7-associated genes across cancer lineages are SRGNP1, SOCS5P3, and MIR548AR. Each is linked with IGLC7 in more than 2 cancer types. Because this analysis shows association rather than direction, both IGLC7-to-partner and partner-to-IGLC7 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IGLC7→partner) and Y-score (partner→IGLC7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	SRGNP1 →	+0.218	+3.178	<.001	.006	3	3
LUAD	SOCS5P3 →	+0.044	+4.194	<.001	.009	3	2
UCEC	MIR548AR →	+1.088	+3.675	.001	.003	3	2
SKCM	OR8G1 →	+0.063	+3.525	<.001	.002	3	2
SKCM	MTND4P30 →	+0.040	+3.560	.001	.002	3	2
SKCM	DBIP2 →	+0.188	+3.071	<.001	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 99 associations by consensus.

Exploration

IGLC7 survival (RNA) · tumor vs normal (RNA) · all IGLC7 data types