Across TCGA patient cohorts, IGLC6 RNA expression is significantly associated with the RNA expression of many other genes, with 9,185 significant associations in total. TGCT shows the largest number of these associations.

The most reproducible IGLC6-associated genes across cancer lineages are IGLV9-49, IGHV3-64, and IGHV4-59. Each is linked with IGLC6 in more than 31 cancer types. Because this analysis shows association rather than direction, both IGLC6-to-partner and partner-to-IGLC6 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IGLC6→partner) and Y-score (partner→IGLC6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	IGLV9-49 →	+3.054	+1.805	<.001	<.001	3	32
ESCA	IGHV3-64 →	+2.380	+1.354	<.001	<.001	3	32
THCA	IGHV4-59 →	+4.556	+1.613	<.001	<.001	3	32
THCA	IGHV3-74 →	+3.860	+1.604	<.001	<.001	3	32
CHOL	IGHV3-72 →	+3.030	+2.073	<.001	.001	3	32
LUSC	IGKV1OR2-108 →	+2.916	+2.091	<.001	<.001	3	32

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,185 associations by consensus.

Exploration

IGLC6 survival (RNA) · tumor vs normal (RNA) · all IGLC6 data types