IGLC5

Across TCGA patient cohorts, IGLC5 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,863 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible IGLC5-associated GO terms across cancer lineages are B cell receptor signaling pathway, Negative regulation of leukocyte apoptotic process, and B cell mediated immunity. Each is linked with IGLC5 in more than 24 cancer types. Because this analysis shows association rather than direction, both IGLC5-to-partner and partner-to-IGLC5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, B cell receptor signaling pathway grouped by IGLC5-low versus IGLC5-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IGLC5→partner) and Y-score (partner→IGLC5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	B cell receptor signaling pathway →	+0.087	+0.607	<.001	<.001	3	25
STAD	Negative regulation of leukocyte apoptotic process →	+0.071	+0.485	<.001	<.001	3	25
THCA	B cell mediated immunity →	+0.101	+0.395	<.001	<.001	3	25
THCA	Antibacterial humoral response →	+0.167	+0.366	<.001	<.001	3	25
SKCM	T cell selection →	+0.068	+0.618	<.001	<.001	3	24
SKCM	Regulation of B cell differentiation →	+0.090	+0.597	<.001	<.001	3	24

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,863 associations by consensus.

B cell receptor signaling pathway by IGLC5 expression — STAD

Explore this box plot interactively →