Across TCGA patient cohorts, IGLC3 mutation is significantly associated with the RNA expression of many other genes, with 36 significant associations in total. DLBC shows the largest number of these associations.

The most reproducible IGLC3-associated genes across cancer lineages are RNU6-1216P, MIR1295A, and RN7SKP159. Each is linked with IGLC3 in more than 1 cancer types. Because this analysis shows association rather than direction, both IGLC3-to-partner and partner-to-IGLC3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IGLC3→partner) and Y-score (partner→IGLC3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
DLBC	RNU6-1216P →	+0.408	+4.459	<.001	<.001	3	1
DLBC	MIR1295A →	+0.404	+3.906	<.001	.009	3	1
DLBC	RN7SKP159 →	+0.144	+3.906	<.001	.009	3	1
DLBC	RPL7L1P1 →	+0.342	+3.655	.001	.005	3	1
DLBC	SLC6A14P3 →	+0.074	+3.906	<.001	.009	3	1
DLBC	S100A11P5 →	+0.236	+4.011	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 36 associations by consensus.

Exploration

IGLC3 survival (RNA) · tumor vs normal (RNA) · all IGLC3 data types