Across TCGA patient cohorts, IGLC2 RNA expression is significantly associated with the RNA expression of many other genes, with 10,155 significant associations in total. TGCT shows the largest number of these associations.

The most reproducible IGLC2-associated genes across cancer lineages are IGLC3, IGHG2, and IGHV2-5. Each is linked with IGLC2 in more than 32 cancer types. Because this analysis shows association rather than direction, both IGLC2-to-partner and partner-to-IGLC2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IGLC2→partner) and Y-score (partner→IGLC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
THCA	IGLC3 →	+5.665	+5.938	<.001	<.001	3	33
THCA	IGHG2 →	+5.989	+5.905	<.001	<.001	3	33
HNSC	IGHV2-5 →	+3.418	+4.074	<.001	<.001	3	33
ESCA	IGHV3-7 →	+2.832	+3.170	<.001	<.001	3	33
THCA	IGHV3-15 →	+5.118	+5.793	<.001	<.001	3	33
SKCM	IGHV3-21 →	+5.291	+5.150	<.001	<.001	3	33

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,155 associations by consensus.

Exploration

IGLC2 survival (RNA) · tumor vs normal (RNA) · all IGLC2 data types