Across TCGA patient cohorts, IGLC2 mutation is significantly associated with the RNA expression of many other genes, with 12 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible IGLC2-associated genes across cancer lineages are SNORA15, SNORA79, and SOX1-OT. Each is linked with IGLC2 in more than 1 cancer types. Because this analysis shows association rather than direction, both IGLC2-to-partner and partner-to-IGLC2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IGLC2→partner) and Y-score (partner→IGLC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
DLBC	SNORA15 →	+0.288	+2.624	.004	.006	3	1
DLBC	SNORA79 →	+0.713	+3.022	.002	.001	3	1
DLBC	SOX1-OT →	+1.036	+3.000	.009	.002	3	1
DLBC	RNVU1-26 →	+1.059	+3.459	<.001	.003	3	1
SKCM	RNA5SP461 →	+0.468	+7.816	<.001	.008	3	1
SKCM	RNU2-19P →	+0.273	+7.816	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

Exploration

IGLC2 survival (RNA) · tumor vs normal (RNA) · all IGLC2 data types