Across TCGA patient cohorts, IGLC2 mutation is significantly associated with the immune_cell of many other genes, with 5 significant associations in total. DLBC shows the largest number of these associations.

The most reproducible IGLC2-associated genes across cancer lineages are Myocytes, Neurons, and Osteoblast. Each is linked with IGLC2 in more than 1 cancer types. Because this analysis shows association rather than direction, both IGLC2-to-partner and partner-to-IGLC2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IGLC2→partner) and Y-score (partner→IGLC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
DLBC	Myocytes →	+0.040	+2.868	.006	.022	2	2
DLBC	Neurons →	+0.026	+2.868	.002	.022	3	1
DLBC	Osteoblast →	+0.020	+1.974	.045	.040	3	1
DLBC	CD4+ memory T-cells →	-0.090	-2.745	.041	.047	3	1
DLBC	Class-switched memory B-cells →	-0.067	-2.745	.034	.047	1	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

Exploration

IGLC2 survival (RNA) · tumor vs normal (RNA) · all IGLC2 data types