IGKV6D-41

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, IGKV6D-41 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,233 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible IGKV6D-41-associated GO terms across cancer lineages are B cell mediated immunity, Immunoglobulin production, and Antibacterial humoral response. Each is linked with IGKV6D-41 in more than 24 cancer types. Because this analysis shows association rather than direction, both IGKV6D-41-to-partner and partner-to-IGKV6D-41 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IGKV6D-41→partner) and Y-score (partner→IGKV6D-41) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
THCAB cell mediated immunity →+0.100+0.357<.001<.001325
STADImmunoglobulin production →+0.083+0.401<.001<.001325
THCAAntibacterial humoral response →+0.163+0.344<.001<.001324
THCAComplement activation, classical pathway →+0.179+0.339<.001<.001324
SKCMB cell receptor signaling pathway →+0.082+0.271<.001<.001323
THCAAntimicrobial humoral response →+0.112+0.337<.001<.001323
Each partner links to its Q-omics profile. Showing the 6 strongest of 6,233 associations by consensus.

Exploration